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Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services

The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active...

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Autores principales: Hu, Zhi-Liang, Park, Carissa A, Reecy, James M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728226/
https://www.ncbi.nlm.nih.gov/pubmed/34850103
http://dx.doi.org/10.1093/nar/gkab1116
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author Hu, Zhi-Liang
Park, Carissa A
Reecy, James M
author_facet Hu, Zhi-Liang
Park, Carissa A
Reecy, James M
author_sort Hu, Zhi-Liang
collection PubMed
description The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active development of the databases over the years to keep up with the rapid advancement of genome sciences. The ongoing development has ensured that these databases provide researchers not only with continually updated data but also with new web tools to disseminate the data. Through our continued efforts, the databases have evolved from the original Pig QTLdb for cross-experiment QTL data comparisons to an Animal QTLdb hosting 220 401 QTL, SNP association and eQTL data linking phenotype to genotype for 2210 traits. In addition, there are 23 552 correlations for 866 traits and 4273 heritability data on 1069 traits in CorrDB. All these data were curated from 3157 publications that cover seven livestock species. Along with the continued data curation, new species, additional genome builds, and new functions and features have been built into the databases as well. Standardized procedures to support data mapping on multiple species/genome builds and the ability to browse data based on linked ontology terms are highlights of the recent developments.
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spelling pubmed-87282262022-01-05 Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services Hu, Zhi-Liang Park, Carissa A Reecy, James M Nucleic Acids Res Database Issue The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active development of the databases over the years to keep up with the rapid advancement of genome sciences. The ongoing development has ensured that these databases provide researchers not only with continually updated data but also with new web tools to disseminate the data. Through our continued efforts, the databases have evolved from the original Pig QTLdb for cross-experiment QTL data comparisons to an Animal QTLdb hosting 220 401 QTL, SNP association and eQTL data linking phenotype to genotype for 2210 traits. In addition, there are 23 552 correlations for 866 traits and 4273 heritability data on 1069 traits in CorrDB. All these data were curated from 3157 publications that cover seven livestock species. Along with the continued data curation, new species, additional genome builds, and new functions and features have been built into the databases as well. Standardized procedures to support data mapping on multiple species/genome builds and the ability to browse data based on linked ontology terms are highlights of the recent developments. Oxford University Press 2021-11-24 /pmc/articles/PMC8728226/ /pubmed/34850103 http://dx.doi.org/10.1093/nar/gkab1116 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Hu, Zhi-Liang
Park, Carissa A
Reecy, James M
Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title_full Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title_fullStr Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title_full_unstemmed Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title_short Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
title_sort bringing the animal qtldb and corrdb into the future: meeting new challenges and providing updated services
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728226/
https://www.ncbi.nlm.nih.gov/pubmed/34850103
http://dx.doi.org/10.1093/nar/gkab1116
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