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Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services
The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728226/ https://www.ncbi.nlm.nih.gov/pubmed/34850103 http://dx.doi.org/10.1093/nar/gkab1116 |
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author | Hu, Zhi-Liang Park, Carissa A Reecy, James M |
author_facet | Hu, Zhi-Liang Park, Carissa A Reecy, James M |
author_sort | Hu, Zhi-Liang |
collection | PubMed |
description | The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active development of the databases over the years to keep up with the rapid advancement of genome sciences. The ongoing development has ensured that these databases provide researchers not only with continually updated data but also with new web tools to disseminate the data. Through our continued efforts, the databases have evolved from the original Pig QTLdb for cross-experiment QTL data comparisons to an Animal QTLdb hosting 220 401 QTL, SNP association and eQTL data linking phenotype to genotype for 2210 traits. In addition, there are 23 552 correlations for 866 traits and 4273 heritability data on 1069 traits in CorrDB. All these data were curated from 3157 publications that cover seven livestock species. Along with the continued data curation, new species, additional genome builds, and new functions and features have been built into the databases as well. Standardized procedures to support data mapping on multiple species/genome builds and the ability to browse data based on linked ontology terms are highlights of the recent developments. |
format | Online Article Text |
id | pubmed-8728226 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-87282262022-01-05 Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services Hu, Zhi-Liang Park, Carissa A Reecy, James M Nucleic Acids Res Database Issue The Animal QTLdb (https://www.animalgenome.org/QTLdb) and CorrDB (https://www.animalgenome.org/CorrDB) are unique resources for livestock animal genetics and genomics research which have been used extensively by the international livestock genome research community. This is largely due to the active development of the databases over the years to keep up with the rapid advancement of genome sciences. The ongoing development has ensured that these databases provide researchers not only with continually updated data but also with new web tools to disseminate the data. Through our continued efforts, the databases have evolved from the original Pig QTLdb for cross-experiment QTL data comparisons to an Animal QTLdb hosting 220 401 QTL, SNP association and eQTL data linking phenotype to genotype for 2210 traits. In addition, there are 23 552 correlations for 866 traits and 4273 heritability data on 1069 traits in CorrDB. All these data were curated from 3157 publications that cover seven livestock species. Along with the continued data curation, new species, additional genome builds, and new functions and features have been built into the databases as well. Standardized procedures to support data mapping on multiple species/genome builds and the ability to browse data based on linked ontology terms are highlights of the recent developments. Oxford University Press 2021-11-24 /pmc/articles/PMC8728226/ /pubmed/34850103 http://dx.doi.org/10.1093/nar/gkab1116 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Issue Hu, Zhi-Liang Park, Carissa A Reecy, James M Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title | Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title_full | Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title_fullStr | Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title_full_unstemmed | Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title_short | Bringing the Animal QTLdb and CorrDB into the future: meeting new challenges and providing updated services |
title_sort | bringing the animal qtldb and corrdb into the future: meeting new challenges and providing updated services |
topic | Database Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728226/ https://www.ncbi.nlm.nih.gov/pubmed/34850103 http://dx.doi.org/10.1093/nar/gkab1116 |
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