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Kincore: a web resource for structural classification of protein kinases and their inhibitors

The active form of kinases is shared across different family members, as are several commonly observed inactive forms. We previously performed a clustering of the conformation of the activation loop of all protein kinase structures in the Protein Data Bank (PDB) into eight classes based on the dihed...

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Detalles Bibliográficos
Autores principales: Modi, Vivek, Dunbrack, Roland L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728253/
https://www.ncbi.nlm.nih.gov/pubmed/34643709
http://dx.doi.org/10.1093/nar/gkab920