DRAM1 increases the secretion of PKM2-enriched EVs from hepatocytes to promote macrophage activation and disease progression in ALD

DNA damage-regulated autophagy modulator 1 (DRAM1) could play important roles in inflammation and hepatic apoptosis, while its roles in alcohol-related liver disease (ALD), which is characterized by hepatic inflammation and apoptosis, are still unclear. In this study, we explored the expression, rol...

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Detalles Bibliográficos
Autores principales: Tan, Jie, Zhang, Jie, Wang, Mengke, Wang, Yifen, Dong, Mengzhen, Ma, Xuefeng, Sun, Baokai, Liu, Shousheng, Zhao, Zhenzhen, Chen, Lizhen, Jin, Wenwen, Liu, Kai, Xin, Yongning, Zhuang, Likun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728309/
https://www.ncbi.nlm.nih.gov/pubmed/35036051
http://dx.doi.org/10.1016/j.omtn.2021.12.017

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