Cargando…

In vivo metabolic effects after acute activation of skeletal muscle G(s) signaling

OBJECTIVE: The goal of this study was to determine the glucometabolic effects of acute activation of G(s) signaling in skeletal muscle (SKM) in vivo and its contribution to whole-body glucose homeostasis. METHODS: To address this question, we studied mice that express a G(s)-coupled designer G prote...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meister, Jaroslawna, Bone, Derek B.J., Knudsen, Jonas R., Barella, Luiz F., Liu, Liu, Lee, Regina, Gavrilova, Oksana, Chen, Min, Weinstein, Lee S., Kleinert, Maximilian, Jensen, Thomas E., Wess, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728399/ https://www.ncbi.nlm.nih.gov/pubmed/34883278 http://dx.doi.org/10.1016/j.molmet.2021.101415

Ejemplares similares

Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells
por: Meister, Jaroslawna, et al.
Publicado: (2022)

Selective activation of G(s) signaling in adipocytes causes striking metabolic improvements in mice
por: Wang, Lei, et al.
Publicado: (2019)

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity
por: Barella, Luiz F., et al.
Publicado: (2021)

β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia
por: Pydi, Sai P., et al.
Publicado: (2020)

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice
por: Meister, Jaroslawna, et al.
Publicado: (2019)

Adipocyte G(i) signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
por: Wang, Lei, et al.
Publicado: (2020)

Novel metabolic role for BDNF in pancreatic β-cell insulin secretion
por: Fulgenzi, Gianluca, et al.
Publicado: (2020)

Beneficial metabolic role of β-arrestin-1 expressed by AgRP neurons
por: Pydi, Sai P., et al.
Publicado: (2020)

Adipocyte G(q) signaling is a regulator of glucose and lipid homeostasis in mice
por: Kimura, Takefumi, et al.
Publicado: (2022)

G(q) signaling in α cells is critical for maintaining euglycemia
por: Liu, Liu, et al.
Publicado: (2021)

OR12-3 Mice with MC4R Site Mutation (F51L) Develop Severe Obesity Independent of G(s)-alpha/cAMP Signaling
por: Metzger, Peter, et al.
Publicado: (2019)

Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
por: Nakajima, Ken-ichiro, et al.
Publicado: (2016)

Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
por: Nakajima, Ken-ichiro, et al.
Publicado: (2016)

G protein-coupled receptors: Role in metabolic disorders
por: Barella, Luiz F., et al.
Publicado: (2022)

Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB(1)R) Antagonist
por: Liu, Ziyi, et al.
Publicado: (2021)

G(s)α deficiency in the dorsomedial hypothalamus leads to obesity, hyperphagia, and reduced thermogenesis associated with impaired leptin signaling
por: Chen, Min, et al.
Publicado: (2019)

Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
por: Kleinert, Maximilian, et al.
Publicado: (2018)

Skeletal manifestations of juvenile hypothyroidism and the impact of treatment on skeletal system
por: Gutch, Manish, et al.
Publicado: (2013)

Rac1 Signaling Is Required for Insulin-Stimulated Glucose Uptake and Is Dysregulated in Insulin-Resistant Murine and Human Skeletal Muscle
por: Sylow, Lykke, et al.
Publicado: (2013)

Adipocyte P2Y(14) receptors play a key role in regulating whole-body glucose and lipid homeostasis
por: Jain, Shanu, et al.
Publicado: (2021)

Dose-response relationships in gene expression profiles in a harbor seal B lymphoma cell line exposed to 17 -ethinyl estradiol
por: Kleinert, Christine, et al.
Publicado: (2017)

Periodized low protein-high carbohydrate diet confers potent, but transient, metabolic improvements
por: Li, Zhencheng, et al.
Publicado: (2018)

Exercise increases circulating GDF15 in humans
por: Kleinert, Maximilian, et al.
Publicado: (2018)

Maxillary protraction using skeletal anchorage and intermaxillary elastics in Skeletal Class III patients
por: Esenlik, Elçin, et al.
Publicado: (2015)

The impact of summer drought on peat soil microbiome structure and function-A multi-proxy-comparison
por: Wang, Haitao, et al.
Publicado: (2022)

Hepatic Muscarinic Acetylcholine Receptors Are Not Critically Involved in Maintaining Glucose Homeostasis in Mice
por: Li, Jian H., et al.
Publicado: (2009)

Long-Term Health-Related Quality of Life and Clinical Outcomes in Patients with β-Thalassemia after Splenectomy
por: Caocci, Giovanni, et al.
Publicado: (2023)

Mitogenomic Research of Silverleaf Sunflower (Helianthus argophyllus) and Its Interspecific Hybrids
por: Makarenko, Maksim S., et al.
Publicado: (2023)

Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle
por: Sylow, Lykke, et al.
Publicado: (2013)

IGF-I Exerts an Anti-inflammatory Effect on Skeletal Muscle Cells through Down-regulation of TLR4 Signaling
por: Lee, Won Jun
Publicado: (2011)

MyoD-positive epiblast cells regulate skeletal muscle differentiation in the embryo
por: Gerhart, Jacquelyn, et al.
Publicado: (2006)

SATELLITE CELL OF SKELETAL MUSCLE FIBERS
por: Mauro, Alexander
Publicado: (1961)

Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
por: Kanta, Josephine M., et al.
Publicado: (2023)

Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training
por: Kleinert, Maximilian, et al.
Publicado: (2018)

Seroprevalence of CMV IgG and IgM in Korean women of childbearing age
por: Choi, Rihwa, et al.
Publicado: (2021)

OCCURRENCE OF CENTRIOLES DURING SKELETAL AND CARDIAC MYOGENESIS
por: Przybylski, Ronald J.
Publicado: (1971)

Predicting skeletal stature using ancient DNA
por: Cox, Samantha L., et al.
Publicado: (2021)

IgG4-associated orbital and ocular inflammation
por: Lee, Cecilia S, et al.
Publicado: (2015)

Transient IgA, steady IgG?
por: Berthold, Dorothée L., et al.
Publicado: (2020)

A study on the relationship between compulsive exercise, depression and anxiety
por: Weinstein, Aviv, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kv14fnsdsdih3p05i5rc3nkbtu