Thiol-based functional mimicry of phosphorylation of the two-component system response regulator ArcA promotes pathogenesis in enteric pathogens

Pathogenic bacteria can rapidly respond to stresses such as reactive oxygen species (ROS) using reversible redox-sensitive oxidation of cysteine thiol (-SH) groups in regulators. Here, we use proteomics to profile reversible ROS-induced thiol oxidation in Vibrio cholerae, the etiologic agent of chol...

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Detalles Bibliográficos
Autores principales: Zhou, Yitian, Pu, Qinqin, Chen, Jiandong, Hao, Guijuan, Gao, Rong, Ali, Afsar, Hsiao, Ansel, Stock, Ann M., Goulian, Mark, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728512/
https://www.ncbi.nlm.nih.gov/pubmed/34936880
http://dx.doi.org/10.1016/j.celrep.2021.110147

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