Anti-EFG1 2′-OMethylRNA oligomer inhibits Candida albicans filamentation and attenuates the candidiasis in Galleria mellonella

EFG1 is a central transcriptional regulator of filamentation that is an important virulence factor of Candida albicans. This study serves to assess in vivo the applicability of the anti-EFG1 2′-OMethylRNA oligomer for inhibiting C.albicans filamentation and to attenuate candidiasis, using the Galler...

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Detalles Bibliográficos
Autores principales: Araújo, Daniela, Mil-Homens, Dalila, Henriques, Mariana, Silva, Sónia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728520/
https://www.ncbi.nlm.nih.gov/pubmed/35036062
http://dx.doi.org/10.1016/j.omtn.2021.12.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728520/
https://www.ncbi.nlm.nih.gov/pubmed/35036062
http://dx.doi.org/10.1016/j.omtn.2021.12.018

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