Silencing IQGAP1 alleviates hepatic fibrogenesis via blocking bone marrow mesenchymal stromal cell recruitment to fibrotic liver

IQ motif-containing guanosine triphosphatase (GTPase)-activating protein 1 (IQGAP1) is a cytosolic scaffolding protein involved in cell migration. Our previous studies suggest sphingosine 1-phosphate (S1P) triggers bone marrow (BM) mesenchymal stromal cells (BMSCs) to damaged liver, thereby promotin...

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Detalles Bibliográficos
Autores principales: Ma, Yuehan, Chang, Na, Liu, Yuran, Liu, Fuquan, Dong, Chengbin, Hou, Lei, Qi, Changbo, Yang, Lin, Li, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728523/
https://www.ncbi.nlm.nih.gov/pubmed/35036058
http://dx.doi.org/10.1016/j.omtn.2021.12.020

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