OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis

BACKGROUND: Gallbladder cancer (GBC) is a highly lethal malignancy that carries an extremely poor prognosis due to its chemoresistant nature. Cisplatin (CDDP) is a first-line chemotherapeutic for GBC; however, patients experienced no benefit when treated with CDDP alone. The underlying mechanisms of...

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Detalles Bibliográficos
Autores principales: Lin, Zhuying, Yang, Songlin, Zhou, Yong, Hou, Zongliu, Li, Lin, Meng, Mingyao, Ge, Chunlei, Zeng, Baozhen, Lai, Jinbao, Gao, Hui, Zhao, Yiyi, Xie, Yanhua, He, Shan, Tang, Weiwei, Li, Ruhong, Tan, Jing, Wang, Wenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728528/
https://www.ncbi.nlm.nih.gov/pubmed/34974280
http://dx.doi.org/10.1016/j.tranon.2021.101331

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