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African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D
African swine fever (ASF) is a viral hemorrhagic disease that affects domestic pigs and wild boar and is caused by the African swine fever virus (ASFV). The ASFV virion contains a long double-stranded DNA genome, which encodes more than 150 proteins. However, the immune escape mechanism and pathogen...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728581/ https://www.ncbi.nlm.nih.gov/pubmed/34890644 http://dx.doi.org/10.1016/j.jbc.2021.101480 |