African swine fever virus cysteine protease pS273R inhibits pyroptosis by noncanonically cleaving gasdermin D

African swine fever (ASF) is a viral hemorrhagic disease that affects domestic pigs and wild boar and is caused by the African swine fever virus (ASFV). The ASFV virion contains a long double-stranded DNA genome, which encodes more than 150 proteins. However, the immune escape mechanism and pathogen...

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Detalles Bibliográficos
Autores principales: Zhao, Gaihong, Li, Tingting, Liu, Xuemin, Zhang, Taoqing, Zhang, Zhaoxia, Kang, Li, Song, Jie, Zhou, Shijun, Chen, Xin, Wang, Xiao, Li, Jiangnan, Huang, Li, Li, Changyao, Bu, Zhigao, Zheng, Jun, Weng, Changjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728581/
https://www.ncbi.nlm.nih.gov/pubmed/34890644
http://dx.doi.org/10.1016/j.jbc.2021.101480

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