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Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure

High fidelity simulations of expiratory events such as coughing provide the opportunity to predict the fate of the droplets from the turbulent jet cloud produced from a cough. It is well established that droplets carrying infectious pathogens with diameters of [Formula: see text] remain suspended in...

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Autores principales: Calmet, Hadrien, Inthavong, Kiao, Both, Ambrus, Surapaneni, Anurag, Mira, Daniel, Egukitza, Beatriz, Houzeaux, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728631/
https://www.ncbi.nlm.nih.gov/pubmed/35002205
http://dx.doi.org/10.1063/5.0072148
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author Calmet, Hadrien
Inthavong, Kiao
Both, Ambrus
Surapaneni, Anurag
Mira, Daniel
Egukitza, Beatriz
Houzeaux, Guillaume
author_facet Calmet, Hadrien
Inthavong, Kiao
Both, Ambrus
Surapaneni, Anurag
Mira, Daniel
Egukitza, Beatriz
Houzeaux, Guillaume
author_sort Calmet, Hadrien
collection PubMed
description High fidelity simulations of expiratory events such as coughing provide the opportunity to predict the fate of the droplets from the turbulent jet cloud produced from a cough. It is well established that droplets carrying infectious pathogens with diameters of [Formula: see text] remain suspended in the air for several hours and transported by the air currents over considerable distances (e.g., in meters). This study used a highly resolved mesh to capture the multiphase turbulent buoyant cloud with suspended droplets produced by a cough. The cough droplets' dispersion was subjected to thermal gradients and evaporation and allowed to disperse between two humans standing 2 m apart. A nasal cavity anatomy was included inside the second human to determine the inhaled droplets. Three diameter ranges characterized the droplet cloud, [Formula: see text] , which made up 93% of all droplets by number; 5 to 100 μm comprised 3%, and [Formula: see text] m comprising 4%. The results demonstrated the temporal evolution of the cough event, where a jet is first formed, followed by a thermally driven puff cloud with the latter primarily composed of droplets under 5 μm diameter, moving with a vortex string structure. After the initial cough, the data were interpolated onto a more coarse mesh to allow the simulation to cover ten minutes, equivalent to 150 breathing cycles. We observe that the critical diameter size susceptible to inhalation was [Formula: see text] , although most inhaled droplets after 10 min by the second human were approximately [Formula: see text]. These observations offer insight into the risk of airborne transmission and numerical metrics for modeling and risk assessment.
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spelling pubmed-87286312022-01-05 Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure Calmet, Hadrien Inthavong, Kiao Both, Ambrus Surapaneni, Anurag Mira, Daniel Egukitza, Beatriz Houzeaux, Guillaume Phys Fluids (1994) ARTICLES High fidelity simulations of expiratory events such as coughing provide the opportunity to predict the fate of the droplets from the turbulent jet cloud produced from a cough. It is well established that droplets carrying infectious pathogens with diameters of [Formula: see text] remain suspended in the air for several hours and transported by the air currents over considerable distances (e.g., in meters). This study used a highly resolved mesh to capture the multiphase turbulent buoyant cloud with suspended droplets produced by a cough. The cough droplets' dispersion was subjected to thermal gradients and evaporation and allowed to disperse between two humans standing 2 m apart. A nasal cavity anatomy was included inside the second human to determine the inhaled droplets. Three diameter ranges characterized the droplet cloud, [Formula: see text] , which made up 93% of all droplets by number; 5 to 100 μm comprised 3%, and [Formula: see text] m comprising 4%. The results demonstrated the temporal evolution of the cough event, where a jet is first formed, followed by a thermally driven puff cloud with the latter primarily composed of droplets under 5 μm diameter, moving with a vortex string structure. After the initial cough, the data were interpolated onto a more coarse mesh to allow the simulation to cover ten minutes, equivalent to 150 breathing cycles. We observe that the critical diameter size susceptible to inhalation was [Formula: see text] , although most inhaled droplets after 10 min by the second human were approximately [Formula: see text]. These observations offer insight into the risk of airborne transmission and numerical metrics for modeling and risk assessment. AIP Publishing LLC 2021-12 2021-12-15 /pmc/articles/PMC8728631/ /pubmed/35002205 http://dx.doi.org/10.1063/5.0072148 Text en © 2021 Author(s). Published under an exclusive license by AIP Publishing. https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle ARTICLES
Calmet, Hadrien
Inthavong, Kiao
Both, Ambrus
Surapaneni, Anurag
Mira, Daniel
Egukitza, Beatriz
Houzeaux, Guillaume
Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title_full Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title_fullStr Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title_full_unstemmed Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title_short Large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
title_sort large eddy simulation of cough jet dynamics, droplet transport, and inhalability over a ten minute exposure
topic ARTICLES
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728631/
https://www.ncbi.nlm.nih.gov/pubmed/35002205
http://dx.doi.org/10.1063/5.0072148
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