Absence of exaggerated pharmacology by recombinant ADAMTS13 in the rat and monkey

Insufficiency of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin motif repeats-13) is the cause of thrombotic thrombocytopenic purpura (TTP) and contributes in microangiopathy in sickle cell disease (SCD). Recombinant ADAMTS13 effectively cleaves prothrombotic ultra-large von Willebr...

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Detalles Bibliográficos
Autores principales: Rossato, Paolo, Glantschnig, Helmut, Leidenmühler, Peter, Kopic, Alexandra, Ruthsatz, Tanja, Majer, Bernhard, Schuster, Maria, Scheiflinger, Friedrich, Höllriegl, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728677/
https://www.ncbi.nlm.nih.gov/pubmed/34267062
http://dx.doi.org/10.1097/MBC.0000000000001064

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