Inferring the distribution of fitness effects in patient-sampled and experimental virus populations: two case studies

We here propose an analysis pipeline for inferring the distribution of fitness effects (DFE) from either patient-sampled or experimentally-evolved viral populations, that explicitly accounts for non-Wright-Fisher and non-equilibrium population dynamics inherent to pathogens. We examine the performan...

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Detalles Bibliográficos
Autores principales: Morales-Arce, Ana Y., Johri, Parul, Jensen, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728706/
https://www.ncbi.nlm.nih.gov/pubmed/34987185
http://dx.doi.org/10.1038/s41437-021-00493-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728706/
https://www.ncbi.nlm.nih.gov/pubmed/34987185
http://dx.doi.org/10.1038/s41437-021-00493-y

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