Cargando…
Inferring the distribution of fitness effects in patient-sampled and experimental virus populations: two case studies
We here propose an analysis pipeline for inferring the distribution of fitness effects (DFE) from either patient-sampled or experimentally-evolved viral populations, that explicitly accounts for non-Wright-Fisher and non-equilibrium population dynamics inherent to pathogens. We examine the performan...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728706/ https://www.ncbi.nlm.nih.gov/pubmed/34987185 http://dx.doi.org/10.1038/s41437-021-00493-y |