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A Reactivity-Based (18)F-Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity

[Image: see text] Oxidative stress underlies the pathology of many human diseases, including the doxorubicin-induced off-target cardiotoxicity in cancer chemotherapies. Since current diagnostic procedures are only capable of monitoring cardiac function, a noninvasive means of detecting biochemical c...

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Detalles Bibliográficos
Autores principales: Mota, Filipa, Pell, Victoria R., Singh, Nisha, Baark, Friedrich, Waters, Edward, Sadasivam, Pragalath, Southworth, Richard, Yan, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728736/
https://www.ncbi.nlm.nih.gov/pubmed/34846906
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00496