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Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review

INTRODUCTION: African women are affected by cancer at an early age of their productivity. However, the exact prevalence and incidence of cancer, including breast cancer is not known in most sub-Saharan African countries, including Ethiopia because of lack of well-established cancer registry. This st...

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Autores principales: Gebretsadik, Achamyelesh, Bogale, Netsanet, Negera, Dereje. G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728771/
https://www.ncbi.nlm.nih.gov/pubmed/34931549
http://dx.doi.org/10.1177/10732748211055262
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author Gebretsadik, Achamyelesh
Bogale, Netsanet
Negera, Dereje. G
author_facet Gebretsadik, Achamyelesh
Bogale, Netsanet
Negera, Dereje. G
author_sort Gebretsadik, Achamyelesh
collection PubMed
description INTRODUCTION: African women are affected by cancer at an early age of their productivity. However, the exact prevalence and incidence of cancer, including breast cancer is not known in most sub-Saharan African countries, including Ethiopia because of lack of well-established cancer registry. This study aims to assess the epidemiology of breast cancer at Hawassa University Comprehensive Specialized Hospital (HUCSH), the biggest referral hospital with cancer treatment center serving the southern part of the country. METHODS: Retrospective review of charts of all patients with a diagnosis of breast cancer between 2013 and 2019 at HUCSH was conducted. A standardized questionnaire was used to collect relevant data that include sociodemographic, symptoms, type of diagnosis, treatment, and outcomes. Data were entered using epidata version 3.1 and analyzed using MS Excel and SPSS version 20. RESULTS: Five hundred fifty-nine (18.6%) breast cancer cases were retrieved in 7 years between 2013 and 2019. Of this, 548 (98%) were women. The median ages of the patents were 38 years. Invasive ductal carcinoma was the leading 309 (55.3%) histologic type followed by 185 (33.1%) lobular carcinoma. One hundred seventy-seven (31.7%) were moderately differentiated and 155 (27.7%) were poorly differentiated. Three hundred seventy-two (66.5%) were advanced breast cancer (Stages III and IV). Trends of breast cancer showed the case load is continuously increasing except with a slight reduction of cases in between 2015 and 2016. The majority were advanced breast cancer occurring at an early age by the time diagnosis made. Invasive ductal carcinomas were the predominant one. The trend also showed a continuous increment of cancer case load. Therefore, cancer registration center establishment, community awareness creation, and intensive early detection strategy are mandatory.
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spelling pubmed-87287712022-01-06 Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review Gebretsadik, Achamyelesh Bogale, Netsanet Negera, Dereje. G Cancer Control Original Research Article INTRODUCTION: African women are affected by cancer at an early age of their productivity. However, the exact prevalence and incidence of cancer, including breast cancer is not known in most sub-Saharan African countries, including Ethiopia because of lack of well-established cancer registry. This study aims to assess the epidemiology of breast cancer at Hawassa University Comprehensive Specialized Hospital (HUCSH), the biggest referral hospital with cancer treatment center serving the southern part of the country. METHODS: Retrospective review of charts of all patients with a diagnosis of breast cancer between 2013 and 2019 at HUCSH was conducted. A standardized questionnaire was used to collect relevant data that include sociodemographic, symptoms, type of diagnosis, treatment, and outcomes. Data were entered using epidata version 3.1 and analyzed using MS Excel and SPSS version 20. RESULTS: Five hundred fifty-nine (18.6%) breast cancer cases were retrieved in 7 years between 2013 and 2019. Of this, 548 (98%) were women. The median ages of the patents were 38 years. Invasive ductal carcinoma was the leading 309 (55.3%) histologic type followed by 185 (33.1%) lobular carcinoma. One hundred seventy-seven (31.7%) were moderately differentiated and 155 (27.7%) were poorly differentiated. Three hundred seventy-two (66.5%) were advanced breast cancer (Stages III and IV). Trends of breast cancer showed the case load is continuously increasing except with a slight reduction of cases in between 2015 and 2016. The majority were advanced breast cancer occurring at an early age by the time diagnosis made. Invasive ductal carcinomas were the predominant one. The trend also showed a continuous increment of cancer case load. Therefore, cancer registration center establishment, community awareness creation, and intensive early detection strategy are mandatory. SAGE Publications 2021-12-21 /pmc/articles/PMC8728771/ /pubmed/34931549 http://dx.doi.org/10.1177/10732748211055262 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Gebretsadik, Achamyelesh
Bogale, Netsanet
Negera, Dereje. G
Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title_full Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title_fullStr Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title_full_unstemmed Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title_short Epidemiological Trends of Breast Cancer in Southern Ethiopia: A Seven-Year Retrospective Review
title_sort epidemiological trends of breast cancer in southern ethiopia: a seven-year retrospective review
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728771/
https://www.ncbi.nlm.nih.gov/pubmed/34931549
http://dx.doi.org/10.1177/10732748211055262
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