Developmental deficits and staging of dynamics of age associated Alzheimer’s disease neurodegeneration and neuronal loss in subjects with Down syndrome

The increased life expectancy of individuals with Down syndrome (DS) is associated with increased prevalence of trisomy 21–linked early-onset Alzheimer’s disease (EOAD) and dementia. The aims of this study of 14 brain regions including the entorhinal cortex, hippocampus, basal ganglia, and cerebellu...

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Detalles Bibliográficos
Autores principales: Wegiel, Jerzy, Flory, Michael, Kuchna, Izabela, Nowicki, Krzysztof, Wegiel, Jarek, Ma, Shuang Yong, Zhong, Nanbert, Bobrowicz, Teresa Wierzba, de Leon, Mony, Lai, Florence, Silverman, Wayne P., Wisniewski, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728914/
https://www.ncbi.nlm.nih.gov/pubmed/34983655
http://dx.doi.org/10.1186/s40478-021-01300-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728914/
https://www.ncbi.nlm.nih.gov/pubmed/34983655
http://dx.doi.org/10.1186/s40478-021-01300-9

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