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Developmental deficits and staging of dynamics of age associated Alzheimer’s disease neurodegeneration and neuronal loss in subjects with Down syndrome
The increased life expectancy of individuals with Down syndrome (DS) is associated with increased prevalence of trisomy 21–linked early-onset Alzheimer’s disease (EOAD) and dementia. The aims of this study of 14 brain regions including the entorhinal cortex, hippocampus, basal ganglia, and cerebellu...
Autores principales: | Wegiel, Jerzy, Flory, Michael, Kuchna, Izabela, Nowicki, Krzysztof, Wegiel, Jarek, Ma, Shuang Yong, Zhong, Nanbert, Bobrowicz, Teresa Wierzba, de Leon, Mony, Lai, Florence, Silverman, Wayne P., Wisniewski, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728914/ https://www.ncbi.nlm.nih.gov/pubmed/34983655 http://dx.doi.org/10.1186/s40478-021-01300-9 |
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