Integrative blood-derived epigenetic and transcriptomic analysis reveals the potential regulatory role of DNA methylation in ankylosing spondylitis

BACKGROUND: The currently known risk loci could explain a small proportion of the heritability of ankylosing spondylitis (AS). Epigenetics might account for the missing heritability. We aimed to seek more novel AS-associated DNA methylation alterations and delineate the regulatory effect of DNA meth...

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Detalles Bibliográficos
Autores principales: Xiao, Min, Zheng, Xuqi, Li, Xiaomin, Wu, Xinyu, Huang, Yefei, Wei, Qiujing, Cao, Shuangyan, Gu, Jieruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728943/
https://www.ncbi.nlm.nih.gov/pubmed/34986893
http://dx.doi.org/10.1186/s13075-021-02697-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728943/
https://www.ncbi.nlm.nih.gov/pubmed/34986893
http://dx.doi.org/10.1186/s13075-021-02697-3

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