Process development and validation of expanded regulatory T cells for prospective applications: an example of manufacturing a personalized advanced therapy medicinal product

BACKGROUND: A growing number of clinical trials have shown that regulatory T (T(reg)) cell transfer may have a favorable effect on the maintenance of self-tolerance and immune homeostasis in different conditions such as graft-versus-host disease (GvHD), solid organ transplantation, type 1 diabetes,...

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Detalles Bibliográficos
Autores principales: Lavazza, Cristiana, Budelli, Silvia, Montelatici, Elisa, Viganò, Mariele, Ulbar, Francesca, Catani, Lucia, Cannone, Marta Giulia, Savelli, Sara, Groppelli, Elisa, Lazzari, Lorenza, Lemoli, Roberto M., Cescon, Matteo, La Manna, Gaetano, Giordano, Rosaria, Montemurro, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729072/
https://www.ncbi.nlm.nih.gov/pubmed/34986854
http://dx.doi.org/10.1186/s12967-021-03200-x

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