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Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16

Since the emergence of SARS-CoV-2 in 2019, Covid-19 has developed into a serious threat to our health, social and economic systems. Although vaccines have been developed in a tour-de-force and are now increasingly available, repurposing of existing drugs has been less successful. There is a clear ne...

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Detalles Bibliográficos
Autores principales: Kozielski, Frank, Sele, Céleste, Talibov, Vladimir O., Lou, Jiaqi, Dong, Danni, Wang, Qian, Shi, Xinyue, Nyblom, Maria, Rogstam, Annika, Krojer, Tobias, Fisher, Zoë, Knecht, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729259/
https://www.ncbi.nlm.nih.gov/pubmed/35128408
http://dx.doi.org/10.1039/d1cb00135c