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Partial Volume Correction Increases the Sensitivity of 18F-Florbetapir-Positron Emission Tomography for the Detection of Early Stage Amyloidosis

Purpose: To test whether correcting for unspecific signal from the cerebral white matter increases the sensitivity of amyloid-PET for early stages of cerebral amyloidosis. Methods: We analyzed 18F-Florbetapir-PET and cerebrospinal fluid (CSF) Aβ42 data from 600 older individuals enrolled in the Alzh...

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Detalles Bibliográficos
Autores principales: Teipel, Stefan J., Dyrba, Martin, Vergallo, Andrea, Lista, Simone, Habert, Marie Odile, Potier, Marie-Claude, Lamari, Foudil, Dubois, Bruno, Hampel, Harald, Grothe, Michel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729321/
https://www.ncbi.nlm.nih.gov/pubmed/35002673
http://dx.doi.org/10.3389/fnagi.2021.748198