Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans

Echinocandins such as caspofungin are frontline antifungal drugs that compromise β-1,3 glucan synthesis in the cell wall. Recent reports have shown that fungal cells can resist killing by caspofungin by upregulation of chitin synthesis, thereby sustaining cell wall integrity (CWI). When echinocandin...

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Detalles Bibliográficos
Autores principales: da Silva Dantas, Alessandra, Nogueira, Filomena, Lee, Keunsook K., Walker, Louise A., Edmondson, Matt, Brand, Alexandra C., Lenardon, Megan D., Gow, Neil A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729787/
https://www.ncbi.nlm.nih.gov/pubmed/34792152
http://dx.doi.org/10.1242/jcs.258889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729787/
https://www.ncbi.nlm.nih.gov/pubmed/34792152
http://dx.doi.org/10.1242/jcs.258889

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