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Generation of oligonucleotide conjugates via one-pot diselenide-selenoester ligation–deselenization/alkylation
A breadth of strategies are needed to efficiently modify oligonucleotides with peptides or lipids to capitalize on their therapeutic and diagnostic potential, including the modulation of in vivo chemical stability and for applications in cell-targeting and cell-permeability. The chemical linkages ty...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8729807/ https://www.ncbi.nlm.nih.gov/pubmed/35126973 http://dx.doi.org/10.1039/d1sc04937b |