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Interleukin-1 receptor on hippocampal neurons drives social withdrawal and cognitive deficits after chronic social stress

Chronic stress contributes to the development of psychiatric disorders including anxiety and depression. Several inflammatory-related effects of stress are associated with increased interleukin-1 (IL-1) signaling within the central nervous system and are mediated by IL-1 receptor 1 (IL-1R1) on sever...

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Detalles Bibliográficos
Autores principales: DiSabato, Damon J., Nemeth, Daniel P., Liu, Xiaoyu, Witcher, Kristina G., O’Neil, Shane M., Oliver, Braedan, Bray, Chelsea E., Sheridan, John F., Godbout, Jonathan P., Quan, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730339/
https://www.ncbi.nlm.nih.gov/pubmed/32444870
http://dx.doi.org/10.1038/s41380-020-0788-3