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Four-dimensional nuclear speckle phase separation dynamics regulate proteostasis

Phase separation and biorhythms control biological processes in the spatial and temporal dimensions, respectively, but mechanisms of four-dimensional integration remain elusive. Here, we identified an evolutionarily conserved XBP1s-SON axis that establishes a cell-autonomous mammalian 12-hour ultrad...

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Detalles Bibliográficos
Autores principales:	Dion, William, Ballance, Heather, Lee, Jane, Pan, Yinghong, Irfan, Saad, Edwards, Casey, Sun, Michelle, Zhang, Jing, Zhang, Xin, Liu, Silvia, Zhu, Bokai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730402/ https://www.ncbi.nlm.nih.gov/pubmed/34985945 http://dx.doi.org/10.1126/sciadv.abl4150

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