Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity

The androgen receptor (AR) plays a central role in prostate cancer. Development of castration resistant prostate cancer (CRPC) requires androgen-independent activation of AR, which involves its large N-terminal domain (NTD) and entails extensive epigenetic changes depending in part on histone lysine...

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Detalles Bibliográficos
Autores principales: Roggero, Carlos M., Esser, Victoria, Duan, Lingling, Rice, Allyson M., Ma, Shihong, Raj, Ganesh V., Rosen, Michael K., Liu, Zhi-Ping, Rizo, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730435/
https://www.ncbi.nlm.nih.gov/pubmed/34986150
http://dx.doi.org/10.1371/journal.pone.0258876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730435/
https://www.ncbi.nlm.nih.gov/pubmed/34986150
http://dx.doi.org/10.1371/journal.pone.0258876

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