Cargando…

Poly-glutamine-dependent self-association as a potential mechanism for regulation of androgen receptor activity

The androgen receptor (AR) plays a central role in prostate cancer. Development of castration resistant prostate cancer (CRPC) requires androgen-independent activation of AR, which involves its large N-terminal domain (NTD) and entails extensive epigenetic changes depending in part on histone lysine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Roggero, Carlos M., Esser, Victoria, Duan, Lingling, Rice, Allyson M., Ma, Shihong, Raj, Ganesh V., Rosen, Michael K., Liu, Zhi-Ping, Rizo, Josep
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730435/ https://www.ncbi.nlm.nih.gov/pubmed/34986150 http://dx.doi.org/10.1371/journal.pone.0258876

Ejemplares similares

Histone lysine demethylase KDM4B regulates the alternative splicing of the androgen receptor in response to androgen deprivation
por: Duan, Lingling, et al.
Publicado: (2019)

A detailed characterization of stepwise activation of the androgen receptor variant 7 in prostate cancer cells
por: Roggero, Carlos M., et al.
Publicado: (2020)

Androgen receptor-mediated non-genomic regulation of prostate cancer cell proliferation
por: Liao, Ross S., et al.
Publicado: (2013)

Glutamine Codon Usage and polyQ Evolution in Primates Depend on the Q Stretch Length
por: Mier, Pablo, et al.
Publicado: (2018)

Oligodendroglioma Cells Lack Glutamine Synthetase and Are Auxotrophic for Glutamine, but Do not Depend on Glutamine Anaplerosis for Growth
por: Chiu, Martina, et al.
Publicado: (2018)

Short androgen receptor poly‐glutamine‐promoted endometrial cancer is associated with benzo[a]pyrene‐mediated aryl hydrocarbon receptor activation
por: Chen, Lumin, et al.
Publicado: (2017)

Dysregulation of core components of SCF complex in poly-glutamine disorders
por: Bhutani, S, et al.
Publicado: (2012)

The association between glutamine repeats in the androgen receptor gene and personality traits in dromedary camel (Camelus dromedarius)
por: Ramadan, Sherif, et al.
Publicado: (2018)

The archaeal transamidosome for RNA-dependent glutamine biosynthesis
por: Rampias, Theodoros, et al.
Publicado: (2010)

Pharmacological Vitamin C Treatment Impedes the Growth of Endogenous Glutamine-Dependent Cancers by Targeting Glutamine Synthetase
por: Long, Yali, et al.
Publicado: (2021)

Synthesis, characterization, and biological evaluation of poly(L-γ-glutamyl-glutamine)- paclitaxel nanoconjugate
por: Van, Sang, et al.
Publicado: (2010)

Glutamine deprivation triggers NAGK-dependent hexosamine salvage
por: Campbell, Sydney, et al.
Publicado: (2021)

Androgen Receptor and Poly(ADP-ribose) Glycohydrolase Inhibition Increases Efficiency of Androgen Ablation in Prostate Cancer Cells
por: Zhang, Manqi, et al.
Publicado: (2020)

Automated synthesis of [(11)C]L-glutamine on Synthra HCN plus synthesis module
por: Padakanti, Prashanth K., et al.
Publicado: (2019)

Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2 Diabetes
por: Dollet, Lucile, et al.
Publicado: (2022)

Dynamic differences between DNA damage repair responses in primary tumors and cell lines
por: Gilbreath, Collin, et al.
Publicado: (2020)

A Poly-Glutamine Region in the Drosophila VAChT Dictates Fill-Level of Cholinergic Synaptic Vesicles
por: Vernon, Samuel W., et al.
Publicado: (2019)

Metabolic Roles of Androgen Receptor and Tip60 in Androgen-Dependent Prostate Cancer
por: Tan, Kah Ni, et al.
Publicado: (2020)

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease
por: Flowers, Ebony M., et al.
Publicado: (2018)

Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
por: Hernandez-Davies, Jenny E, et al.
Publicado: (2015)

Resistance to BRAF inhibitors induces glutamine dependency in melanoma cells
por: Baenke, Franziska, et al.
Publicado: (2015)

Glutamine metabolism, the Achilles heel for medulloblastoma tumor
por: Niklison-Chirou, Maria Victoria
Publicado: (2018)

Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer
por: Henzler, Christine, et al.
Publicado: (2016)

MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
por: Fets, Louise, et al.
Publicado: (2018)

Regulation of expression of Na(+),K(+)-ATPase in androgen-dependent and androgen-independent prostate cancer
por: Blok, L J, et al.
Publicado: (1999)

Glutamine as an Immunonutrient
por: Kim, Hyeyoung
Publicado: (2011)

Glutamine supplementation
por: Wernerman, Jan
Publicado: (2011)

CLONAL DIFFERENCES IN GLUTAMINE SYNTHETASE ACTIVITY OF HEPATOMA CELLS : Effects of Glutamine and Dexamethasone
por: Kulka, Richard G., et al.
Publicado: (1972)

The Role of Androgen Receptor and microRNA Interactions in Androgen-Dependent Diseases
por: Bielska, Agnieszka, et al.
Publicado: (2022)

Rethinking glutamine metabolism and the regulation of glutamine addiction by oncogenes in cancer
por: Ni, Rui, et al.
Publicado: (2023)

Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes
por: Whan, Vicki, et al.
Publicado: (2010)

Poly-L-glutamate/glutamine synthesis in the cell wall of Mycobacterium bovis is regulated in response to nitrogen availability
por: Tripathi, Deeksha, et al.
Publicado: (2013)

Stretch stress propels glutamine dependency and glycolysis in optic nerve head astrocytes
por: Pappenhagen, Nathaniel, et al.
Publicado: (2022)

A glutamine riboswitch is a key element for the regulation of glutamine synthetase in cyanobacteria
por: Klähn, Stephan, et al.
Publicado: (2018)

Ca(2+)-dependent release of synaptotagmin-1 from the SNARE complex on phosphatidylinositol 4,5-bisphosphate-containing membranes
por: Voleti, Rashmi, et al.
Publicado: (2020)

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription
por: Abankwa, Daniel, et al.
Publicado: (2013)

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
por: Yuneva, Mariia, et al.
Publicado: (2007)

Pancreatic cancers depend on a non-canonical glutamine metabolism pathway
por: Lyssiotis, Costas, et al.
Publicado: (2014)

Glutamine deprivation stimulates mTOR-JNK-dependent chemokine secretion
por: Shanware, Naval P., et al.
Publicado: (2014)

Hydrogen Bonding in a l-Glutamine-Based Polyamidoamino Acid and its pH-Dependent Self-Ordered Coil Conformation
por: Lazzari, Federica, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5en87cf2nu819nd427145ge6os