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COVID-19 vaccine and autoimmunity. A new case of autoimmune hepatitis and review of the literature

Autoimmunity following COVID-19 vaccination has been reported. Herein, a 79-year-old man with clinical and immunological features of autoimmune hepatitis type 1 after ChAdOx1 nCoV-19 vaccination is presented. Clinical manifestations rapidly remitted after the instauration of immunomodulatory managem...

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Detalles Bibliográficos
Autores principales: Camacho-Domínguez, Laura, Rodríguez, Yhojan, Polo, Fernando, Restrepo Gutierrez, Juan Carlos, Zapata, Elizabeth, Rojas, Manuel, Anaya, Juan-Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730708/
https://www.ncbi.nlm.nih.gov/pubmed/35013724
http://dx.doi.org/10.1016/j.jtauto.2022.100140
Descripción
Sumario:Autoimmunity following COVID-19 vaccination has been reported. Herein, a 79-year-old man with clinical and immunological features of autoimmune hepatitis type 1 after ChAdOx1 nCoV-19 vaccination is presented. Clinical manifestations rapidly remitted after the instauration of immunomodulatory management. This case, together with a comprehensive review of the literature, illustrates the association between COVID-19 vaccines and the development of autoimmune conditions.