Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS–Hook–FHIP complexes

In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins. While ~40 kinesins transport cargo toward the plus end of microtubules, a single dynein moves cargo in the opposite direc...

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Detalles Bibliográficos
Autores principales: Christensen, Jenna R, Kendrick, Agnieszka A, Truong, Joey B, Aguilar-Maldonado, Adriana, Adani, Vinit, Dzieciatkowska, Monika, Reck-Peterson, Samara L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8730729/
https://www.ncbi.nlm.nih.gov/pubmed/34882091
http://dx.doi.org/10.7554/eLife.74538

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