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CRISPRi links COVID-19 GWAS loci to LZTFL1 and RAVER1

BACKGROUND: To identify host genetic variants (SNPs) associated with COVID-19 disease severity, a number of genome-wide association studies (GWAS) have been conducted. Since most of the identified variants are located at non-coding regions, such variants are presumed to affect the expression of neig...

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Detalles Bibliográficos
Autores principales: Fink-Baldauf, Iris M., Stuart, William D., Brewington, John J., Guo, Minzhe, Maeda, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8731227/
https://www.ncbi.nlm.nih.gov/pubmed/34998241
http://dx.doi.org/10.1016/j.ebiom.2021.103806

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