Cargando…

miR-10b-5p Suppresses the Proliferation and Invasion of Primary Hepatic Carcinoma Cells by Downregulating EphA2

OBJECTIVE: To analyze the function of miR-10b-5p in suppressing the invasion and proliferation of primary hepatic carcinoma cells by downregulating erythropoietin-producing hepatocellular receptor A2 (EphA2). Material and Methods. Eighty-six hepatic carcinoma (HCC) tissue specimens and 86 correspond...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niu, Xu, Sun, Haitao, Qiu, Feng, Liu, Jing, Yang, Tianchi, Han, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8731268/ https://www.ncbi.nlm.nih.gov/pubmed/35005012 http://dx.doi.org/10.1155/2021/1382061

Ejemplares similares

TR(4) nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression
por: Jin, Ren’an, et al.
Publicado: (2018)

Downregulation of EphA5 by promoter methylation in human prostate cancer
por: Li, Shibao, et al.
Publicado: (2015)

Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration
por: Peng, Jing, et al.
Publicado: (2021)

EphA5 and EphA6: regulation of neuronal and spine morphology
por: Das, Gitanjali, et al.
Publicado: (2016)

Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival
por: Gajdzis, Malgorzata, et al.
Publicado: (2020)

miR-141 inhibits glioma vasculogenic mimicry by controlling EphA2 expression
por: Li, Guoxiong, et al.
Publicado: (2018)

EphA2 bears plasticity to tumor invasion
por: Sugiyama, Nami, et al.
Publicado: (2013)

miR-26b enhances radiosensitivity of hepatocellular carcinoma cells by targeting EphA2
por: Jin, Qiao, et al.
Publicado: (2016)

The relationship between miR-302b and EphA2 and their clinical significance in gastric cancer
por: Tang, Lanhua, et al.
Publicado: (2018)

Vaccination with EphA2-derived T cell-epitopes promotes immunity against both EphA2-expressing and EphA2-negative tumors
por: Hatano, Manabu, et al.
Publicado: (2004)

Exosomal MicroRNA-10a Is Associated with Liver Regeneration in Rats through Downregulation of EphA4
por: Luo, Lin, et al.
Publicado: (2018)

EphA2 enhances the proliferation and invasion ability of LNCaP prostate cancer cells
por: CHEN, PEIJIE, et al.
Publicado: (2014)

Targeting EphA2 in cancer
por: Xiao, Ta, et al.
Publicado: (2020)

The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size
por: Zapata-Mercado, Elmer, et al.
Publicado: (2022)

HDAC7 promotes the oncogenicity of nasopharyngeal carcinoma cells by miR-4465-EphA2 signaling axis
por: Li, Qi-Guang, et al.
Publicado: (2020)

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia
por: Charmsaz, Sara, et al.
Publicado: (2015)

miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1
por: Li, Chang-Hui, et al.
Publicado: (2017)

miR-150 is downregulated in osteosarcoma and suppresses cell proliferation, migration and invasion by targeting ROCK1
por: Li, Chang-Hui, et al.
Publicado: (2022)

Roles of EphA2 in Development and Disease
por: Park, Jeong Eun, et al.
Publicado: (2013)

Inhibition of EphA2 by Dasatinib Suppresses Radiation-Induced Intestinal Injury
por: Kim, Areumnuri, et al.
Publicado: (2020)

The EphA1 and EphA2 Signaling Modulates the Epithelial Permeability in Human Sinonasal Epithelial Cells and the Rhinovirus Infection Induces Epithelial Barrier Dysfunction via EphA2 Receptor Signaling
por: Shin, Jae Min, et al.
Publicado: (2023)

Effects of lncRNA HOXA11-AS on Sevoflurane-Induced Neuronal Apoptosis and Inflammatory Responses by Regulating miR-98-5p/EphA4
por: Zhao, Li, et al.
Publicado: (2023)

The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs
por: Liang, Lung-Yu, et al.
Publicado: (2021)

Downregulation of EphA2 stability by RNF5 limits its tumor-suppressive function in HER2-negative breast cancers
por: Li, Xiaojuan, et al.
Publicado: (2023)

miR‐204 downregulates EphB2 in aging mouse hippocampal neurons
por: Danka Mohammed, Chand Parvez, et al.
Publicado: (2016)

Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model
por: Bhatia, Shilpa, et al.
Publicado: (2015)

Protein kinase A can block EphA2 receptor–mediated cell repulsion by increasing EphA2 S897 phosphorylation
por: Barquilla, Antonio, et al.
Publicado: (2016)

Development of an In-House EphA2 ELISA for Human Serum and Measurement of Circulating Levels of EphA2 in Hypertensive Patients with Renal Dysfunction
por: Murakoshi, Maki, et al.
Publicado: (2022)

Drug-resistant cancer cell-derived exosomal EphA2 promotes breast cancer metastasis via the EphA2-Ephrin A1 reverse signaling
por: Gao, Zicong, et al.
Publicado: (2021)

miR-429 suppresses cell proliferation, migration and invasion in nasopharyngeal carcinoma by downregulation of TLN1
por: Wang, Zhihui, et al.
Publicado: (2019)

miR-302 Suppresses the Proliferation, Migration, and Invasion of Breast Cancer Cells by Downregulating ATAD2
por: Hwang, Yo Sep, et al.
Publicado: (2022)

A Novel Occulta-Type Spina Bifida Mediated by Murine Double Heterozygotes EphA2 and EphA4 Receptor Tyrosine Kinases
por: Abdullah, Nor Linda, et al.
Publicado: (2017)

EphA2 and EGFR: Friends in Life, Partners in Crime. Can EphA2 Be a Predictive Biomarker of Response to Anti-EGFR Agents?
por: Cioce, Mario, et al.
Publicado: (2021)

Antibody-mediated depletion of CCR10(+)EphA3(+) cells ameliorates fibrosis in IPF
por: Hohmann, Miriam S., et al.
Publicado: (2021)

Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression
por: Vail, Mary E., et al.
Publicado: (2023)

miR-204 Regulates Cell Proliferation and Invasion by Targeting EphB2 in Human Cervical Cancer
por: Duan, Shanhong, et al.
Publicado: (2018)

Y772 phosphorylation of EphA2 is responsible for EphA2-dependent NPC nasopharyngeal carcinoma growth by Shp2/Erk-1/2 signaling pathway
por: Xiang, Yi-Ping, et al.
Publicado: (2020)

EphA3 Functions are Regulated by Collaborating Phosphotyrosine Residues
por: Shi, Guanfang, et al.
Publicado: (2010)

EphA4 is a prognostic factor in gastric cancer
por: Miyazaki, Kohji, et al.
Publicado: (2013)

Unliganded EphA3 dimerization promoted by the SAM domain
por: Singh, Deo R., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_lalul6h4a9mu3t90c7scnqdtop