The scaffold-dependent function of RIPK1 in dendritic cells promotes injury-induced colitis

Receptor interacting protein kinase 1 (RIPK1) is a cytosolic multidomain protein that controls cell life and death. While RIPK1 promotes cell death through its kinase activity, it also functions as a scaffold protein to promote cell survival by inhibiting FADD-caspase 8-dependent apoptosis and RIPK3...

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Detalles Bibliográficos
Autores principales: Moriwaki, Kenta, Park, Christa, Koyama, Kazuha, Balaji, Sakthi, Kita, Kohei, Yagi, Ryoko, Komazawa-Sakon, Sachiko, Semba, Manami, Asuka, Tatsuya, Nakano, Hiroyasu, Kamada, Yoshihiro, Miyoshi, Eiji, Chan, Francis K. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732271/
https://www.ncbi.nlm.nih.gov/pubmed/34462571
http://dx.doi.org/10.1038/s41385-021-00446-y

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