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The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism

The heightened cardiovascular disease (CVD) risk observed with omnivores is thought to be linked, in part, to gut microbiota-dependent generation trimethylamine-N-oxide (TMAO) from L-carnitine, a nutrient abundant in red meat. Gut microbial transformation of L-carnitine into trimethylamine (TMA), th...

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Detalles Bibliográficos
Autores principales:	Buffa, Jennifer A., Romano, Kymberleigh A., Copeland, Matthew F., Cody, David B., Zhu, Weifei, Galvez, Rachel, Fu, Xiaoming, Ward, Kathryn, Ferrell, Marc, Dai, Hong J., Skye, Sarah, Hu, Ping, Li, Lin, Parlov, Mirjana, McMillan, Amy, Wei, Xingtao, Nemet, Ina, Koeth, Robert A., Li, Xinmin S., Wang, Zeneng, Sangwan, Naseer, Hajjar, Adeline M., Dwidar, Mohammed, Weeks, Taylor L., Bergeron, Nathalie, Krauss, Ronald M., Tang, W.H. Wilson, Rey, Federico E., DiDonato, Joseph A., Gogonea, Valentin, Gerberick, G. Frank, Garcia-Garcia, Jose Carlos, Hazen, Stanley L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732312/ https://www.ncbi.nlm.nih.gov/pubmed/34949826 http://dx.doi.org/10.1038/s41564-021-01010-x

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