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Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma: a prospective study
Treatment of glioblastoma (GBM) remains a challenging task, with limited treatment options, none offering a cure. Immune therapy has proven effective across different cancers with remarkable response rates. Tumor mutational burden (TMB) is a marker of response, but technical and methodological diffe...
Autores principales: | Schou Nørøxe, Dorte, Flynn, Aidan, Westmose Yde, Christina, Østrup, Olga, Cilius Nielsen, Finn, Skjøth‐Rasmussen, Jane, Brennum, Jannick, Hamerlik, Petra, Weischenfeldt, Joachim, Skovgaard Poulsen, Hans, Lassen, Ulrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732341/ https://www.ncbi.nlm.nih.gov/pubmed/34018316 http://dx.doi.org/10.1002/1878-0261.13015 |
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