Cargando…

PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma‐initiating cell properties via DNA methyltransferase 3A

Glioma‐initiating cells (GICs), a major source of glioblastoma recurrence, are characterized by the expression of neural stem cell markers and the ability to grow by forming nonadherent spheres under serum‐free conditions. Bone morphogenetic proteins (BMPs), members of the transforming growth factor...

Descripción completa

Detalles Bibliográficos
Autores principales: Tanabe, Ryo, Miyazono, Kohei, Todo, Tomoki, Saito, Nobuhito, Iwata, Caname, Komuro, Akiyoshi, Sakai, Satoshi, Raja, Erna, Koinuma, Daizo, Morikawa, Masato, Westermark, Bengt, Heldin, Carl‐Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732353/
https://www.ncbi.nlm.nih.gov/pubmed/34214250
http://dx.doi.org/10.1002/1878-0261.13051