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PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma‐initiating cell properties via DNA methyltransferase 3A
Glioma‐initiating cells (GICs), a major source of glioblastoma recurrence, are characterized by the expression of neural stem cell markers and the ability to grow by forming nonadherent spheres under serum‐free conditions. Bone morphogenetic proteins (BMPs), members of the transforming growth factor...
Autores principales: | Tanabe, Ryo, Miyazono, Kohei, Todo, Tomoki, Saito, Nobuhito, Iwata, Caname, Komuro, Akiyoshi, Sakai, Satoshi, Raja, Erna, Koinuma, Daizo, Morikawa, Masato, Westermark, Bengt, Heldin, Carl‐Henrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732353/ https://www.ncbi.nlm.nih.gov/pubmed/34214250 http://dx.doi.org/10.1002/1878-0261.13051 |
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