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Pembrolizumab plus axitinib versus sunitinib in metastatic renal cell carcinoma: outcomes of Japanese patients enrolled in the randomized, phase III, open-label KEYNOTE-426 study
BACKGROUND: In the phase III open-label KEYNOTE-426 (NCT02853331) study, first-line pembrolizumab and axitinib improved overall survival (OS) and progression-free survival (PFS) versus sunitinib for metastatic renal cell carcinoma (mRCC). KEYNOTE-426 evaluated patients enrolled from 25 sites in Japa...
Autores principales: | Tamada, Satoshi, Kondoh, Chihiro, Matsubara, Nobuaki, Mizuno, Ryuichi, Kimura, Go, Anai, Satoshi, Tomita, Yoshihiko, Oyama, Masafumi, Masumori, Naoya, Kojima, Takahiro, Matsumoto, Hiroaki, Chen, Mei, Li, Mengran, Matsuda, Kenji, Tanaka, Yoshinobu, Rini, Brian I., Uemura, Hirotsugu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732816/ https://www.ncbi.nlm.nih.gov/pubmed/34800178 http://dx.doi.org/10.1007/s10147-021-02014-7 |
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