Modeling SARS-CoV-2 spike/ACE2 protein–protein interactions for predicting the binding affinity of new spike variants for ACE2, and novel ACE2 structurally related human protein targets, for COVID-19 handling in the 3PM context

AIMS: The rapid spread of new SARS-CoV-2 variants has highlighted the crucial role played in the infection by mutations occurring at the SARS-CoV-2 spike receptor binding domain (RBD) in the interactions with the human ACE2 receptor. In this context, it urgently needs to develop new rapid tools for...

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Detalles Bibliográficos
Autores principales: Tragni, Vincenzo, Preziusi, Francesca, Laera, Luna, Onofrio, Angelo, Mercurio, Ivan, Todisco, Simona, Volpicella, Mariateresa, De Grassi, Anna, Pierri, Ciro Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8732965/
https://www.ncbi.nlm.nih.gov/pubmed/35013687
http://dx.doi.org/10.1007/s13167-021-00267-w

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