Cargando…

Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes

OBJECTIVES: Loss of functional β-cell mass is a key factor contributing to poor glycemic control in advanced type 2 diabetes (T2D). We have previously reported that the inhibition of the neuropeptide Y1 receptor improves the islet transplantation outcome in type 1 diabetes (T1D). The aim of this stu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Chieh-Hsin, Ann-Onda, Danise, Lin, Xuzhu, Fynch, Stacey, Nadarajah, Shaktypreya, Pappas, Evan G., Liu, Xin, Scott, John W., Oakhill, Jonathan S., Galic, Sandra, Shi, Yanchuan, Moreno-Asso, Alba, Smith, Cassandra, Loudovaris, Thomas, Levinger, Itamar, Eizirik, Decio L., Laybutt, D. Ross, Herzog, Herbert, Thomas, Helen E., Loh, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733231/
https://www.ncbi.nlm.nih.gov/pubmed/34890851
http://dx.doi.org/10.1016/j.molmet.2021.101413