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Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes
OBJECTIVES: Loss of functional β-cell mass is a key factor contributing to poor glycemic control in advanced type 2 diabetes (T2D). We have previously reported that the inhibition of the neuropeptide Y1 receptor improves the islet transplantation outcome in type 1 diabetes (T1D). The aim of this stu...
Autores principales: | Yang, Chieh-Hsin, Ann-Onda, Danise, Lin, Xuzhu, Fynch, Stacey, Nadarajah, Shaktypreya, Pappas, Evan G., Liu, Xin, Scott, John W., Oakhill, Jonathan S., Galic, Sandra, Shi, Yanchuan, Moreno-Asso, Alba, Smith, Cassandra, Loudovaris, Thomas, Levinger, Itamar, Eizirik, Decio L., Laybutt, D. Ross, Herzog, Herbert, Thomas, Helen E., Loh, Kim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733231/ https://www.ncbi.nlm.nih.gov/pubmed/34890851 http://dx.doi.org/10.1016/j.molmet.2021.101413 |
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