Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers

Broadly neutralizing antibodies (bNAbs), known to mediate immune control of HIV-1 infection, only develop in a small subset of HIV-1 infected individuals. Despite being traditionally associated with patients with high viral loads, bNAbs have also been observed in therapy naïve HIV-1+ patients natura...

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Detalles Bibliográficos
Autores principales: Nyanhete, Tinashe E., Edwards, Robert J., LaBranche, Celia C., Mansouri, Katayoun, Eaton, Amanda, Dennison, S. Moses, Saunders, Kevin O., Goodman, Derrick, Janowska, Katarzyna, Spreng, Rachel L., Zhang, Lu, Mudrak, Sarah V., Hope, Thomas J., Hora, Bhavna, Bradley, Todd, Georgiev, Ivelin S., Montefiori, David C., Acharya, Priyamvada, Tomaras, Georgia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733328/
https://www.ncbi.nlm.nih.gov/pubmed/35003053
http://dx.doi.org/10.3389/fimmu.2021.670561

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