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Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study)

BACKGROUND: The long-term efficacy and safety of mepolizumab for treatment of severe eosinophilic asthma are well established. Here, we examine the clinical impact of stopping mepolizumab after long-term use. METHODS: COMET (NCT02555371) was a randomised, double-blind, placebo-controlled, parallel-g...

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Detalles Bibliográficos
Autores principales: Moore, Wendy C., Kornmann, Oliver, Humbert, Marc, Poirier, Claude, Bel, Elisabeth H., Kaneko, Norihiro, Smith, Steven G., Martin, Neil, Gilson, Martyn J., Price, Robert G., Bradford, Eric S., Liu, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733344/
https://www.ncbi.nlm.nih.gov/pubmed/34172470
http://dx.doi.org/10.1183/13993003.00396-2021