STRIDE: a command-line HMM-based identifier and sub-classifier of Plasmodium falciparum RIFIN and STEVOR variant surface antigen families

BACKGROUND: RIFINs and STEVORs are variant surface antigens expressed by P. falciparum that play roles in severe malaria pathogenesis and immune evasion. These two highly diverse multigene families feature multiple paralogs, making their classification challenging using traditional bioinformatic met...

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Detalles Bibliográficos
Autores principales: Zhou, Albert E., Shah, Zalak V., Bradwell, Katie R., Munro, James B., Berry, Andrea A., Serre, David, Takala-Harrison, Shannon, O’Connor, Timothy D., Silva, Joana C., Travassos, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733436/
https://www.ncbi.nlm.nih.gov/pubmed/34991452
http://dx.doi.org/10.1186/s12859-021-04515-8

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