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pH Low Insertion Peptide-Modified Programmed Cell Death-Ligand 1 Potently Suppresses T-Cell Activation Under Acidic Condition

Programmed cell death-ligand 1 (PD-L1)/PD-1 axis is critical for maintenance of immune homeostasis by limiting overactivation of effector T-cell responses. The impairment of PD-L1/PD-1 signals play an important role in the pathogenesis of inflammatory diseases, making this pathway an ideal target fo...

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Detalles Bibliográficos
Autores principales:	Sun, Ying, Hu, Linhan, Yang, Peng, Zhang, Min, Wang, Xinwei, Xiao, He, Qiao, Chunxia, Wang, Jing, Luo, Longlong, Feng, Jiannan, Zheng, Yuanqiang, Wang, Yi, Shi, Yanchun, Chen, Guojiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733706/ https://www.ncbi.nlm.nih.gov/pubmed/35003115 http://dx.doi.org/10.3389/fimmu.2021.794226

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