LC-MS/MS Method for Determination of Hydroxychloroquine and Metabolites: Application in a Pharmacokinetic Study

Hydroxychloroquine (HCQ) was originally used as an antimalarial and immunomodulation drug. We developed and validated a simple and sensitive ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for simultaneous quantitation of HCQ and its three metabolites in rat...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Lili, Wang, Zhipeng, Qiu, Shi, Zhang, Mengwei, Liu, Yanping, Xu, Fengjing, Song, Xinhua, Gao, Shouhong, Chen, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733715/
https://www.ncbi.nlm.nih.gov/pubmed/35003822
http://dx.doi.org/10.1155/2022/6058445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733715/
https://www.ncbi.nlm.nih.gov/pubmed/35003822
http://dx.doi.org/10.1155/2022/6058445

Ejemplares similares