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Crystal structure of CmABCB1 multi-drug exporter in lipidic mesophase revealed by LCP-SFX

CmABCB1 is a Cyanidioschyzon merolae homolog of human ABCB1, a well known ATP-binding cassette (ABC) transporter responsible for multi-drug resistance in various cancers. Three-dimensional structures of ABCB1 homologs have revealed the snapshots of inward- and outward-facing states of the transporte...

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Detalles Bibliográficos
Autores principales: Pan, Dongqing, Oyama, Ryo, Sato, Tomomi, Nakane, Takanori, Mizunuma, Ryo, Matsuoka, Keita, Joti, Yasumasa, Tono, Kensuke, Nango, Eriko, Iwata, So, Nakatsu, Toru, Kato, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733880/
https://www.ncbi.nlm.nih.gov/pubmed/35059217
http://dx.doi.org/10.1107/S2052252521011611