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Host tp53 mutation induces gut dysbiosis eliciting inflammation through disturbed sialic acid metabolism

BACKGROUND: Host tp53 mutations are frequently found during the early stages of colitis-associated colorectal cancer (CAC), but whether such mutations induce gut microbiota dysbiosis and chronic intestinal inflammation that contributes to the development of CAC, remains unknown. RESULTS: We found th...

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Detalles Bibliográficos
Autores principales:	Lee, Jae-Geun, Lee, Soohyun, Jeon, Juhee, Kong, Hyun Gi, Cho, Hyun-Ju, Kim, Jong-Hwan, Kim, Seon-Young, Oh, Myung Jin, Lee, Daum, Seo, Nari, Park, Ki Hun, Yu, Kweon, An, Hyun Joo, Ryu, Choong-Min, Lee, Jeong-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733924/ https://www.ncbi.nlm.nih.gov/pubmed/34991725 http://dx.doi.org/10.1186/s40168-021-01191-x

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