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Identification of polo‐like kinase 1 as a therapeutic target in murine lupus
INTRODUCTION: The signalling cascades that contribute to lupus pathogenesis are incompletely understood. We address this by using an unbiased activity‐based kinome screen of murine lupus. METHODS: An unbiased activity‐based kinome screen (ABKS) of 196 kinases was applied to two genetically different...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733964/ https://www.ncbi.nlm.nih.gov/pubmed/35024139 http://dx.doi.org/10.1002/cti2.1362 |