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Identification of polo‐like kinase 1 as a therapeutic target in murine lupus

INTRODUCTION: The signalling cascades that contribute to lupus pathogenesis are incompletely understood. We address this by using an unbiased activity‐based kinome screen of murine lupus. METHODS: An unbiased activity‐based kinome screen (ABKS) of 196 kinases was applied to two genetically different...

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Detalles Bibliográficos
Autores principales: Li, Yaxi, Wang, Hongting, Zhang, Zijing, Tang, Chenling, Zhou, Xinjin, Mohan, Chandra, Wu, Tianfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733964/
https://www.ncbi.nlm.nih.gov/pubmed/35024139
http://dx.doi.org/10.1002/cti2.1362