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Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment

The tumor microenvironment (TME) is characterized by the activation of immune checkpoints, which limit the ability of immune cells to attack the growing cancer. To overcome immune suppression in the clinic, antigen-expressing viruses and bacteria have been developed to induce antitumor immunity. How...

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Detalles Bibliográficos
Autores principales:	Guo, Fengguang, Das, Jugal K, Kobayashi, Koichi S, Qin, Qing-Ming, A Ficht, Thomas, Alaniz, Robert C, Song, Jianxun, Figueiredo, Paul De
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Oncolytic and Local Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734016/ https://www.ncbi.nlm.nih.gov/pubmed/34987022 http://dx.doi.org/10.1136/jitc-2021-003760

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